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UR-PI376

CAT: 0804-HY-120531Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-120531Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
UR-PI376 is a potent and selective histamine H4 receptor (H4R) agonist with a pEC50 value of 7.47. UR-PI376 shows negligible hH1R and hH2R activities and moderate inverse agonistic activity at the hH3R[1].
CAS Number
1192559-94-6
UNSPSC
12352005
Target
Histamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ur-pi376.html
Smiles
N#CN/C(NCCSC1=CC=CC=C1)=N\CCCCC2=CN=CN2
Molecular Formula
C17H22N6S
Molecular Weight
342.46
References & Citations
[1]Patrick Igel, et al. Synthesis and structure-activity relationships of cyanoguanidine-type and structurally related histamine H4 receptor agonists. J Med Chem. 2009 Oct 22;52 (20) :6297-313.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
H4 Receptor

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