UR-AK49

CAT: 0804-HY-167897Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-167897Size:1 Each
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Description
UR-AK49 (compound 11) is a human histamine H1 and H2 receptor agonist. UR-AK49 has an EC50 of 23 nM in a GTPase assay with hH2R-Gsalpha fusion protein expressed in Sf9 insect cells. UR-AK49 can be used in neuro-related research[1].
CAS Number
[902154-32-9]
UNSPSC
12352005
Target
Histamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ur-ak49.html
Smiles
O=C(CCC1CCCCC1)NC(NCCCC2=CN=CN2)=N
Molecular Formula
C16H27N5O
Molecular Weight
305.42
References & Citations
[1]Xie SX, et al. N1- (3-cyclohexylbutanoyl) -N2-[3- (1H-imidazol-4-yl) propyl]guanidine (UR-AK57), a potent partial agonist for the human histamine H1- and H2-receptors. J Pharmacol Exp Ther. 2006 Jun;317 (3) :1262-8.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
H1 Receptor; H2 Receptor

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