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(E/Z) -NiCur

CAT: 0804-HY-139149A-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-139149A-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
(E/Z) -NiCur is the active isomer of NiCur. (E/Z) -NiCur is a potent CBP histone acetyltransferase (HAT) inhibitor[1].
CAS Number
63476-70-0
UNSPSC
12352005
Target
Histone Acetyltransferase
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/e-z-nicur.html
Smiles
N#CC1=CC=CC(/C=C2C(/C(CCC/2)=C/C3=CC(C#N)=CC=C3)=O)=C1
Molecular Formula
C22H16N2O
Molecular Weight
324.38
References & Citations
[1]Vincek AS, et al. Inhibitor of CBP Histone Acetyltransferase Downregulates p53 Activation and Facilitates Methylation at Lysine 27 on Histone H3. Molecules. 2018;23 (8) :1930. Published 2018 Aug 2.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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