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(E/Z) -ZL0420

CAT: 0804-HY-112149A-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-112149A-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
(E/Z) -ZL0420 is a racemic compound of (Z) -ZL0420 and (E) -ZL0420 isomers. (E) -ZL0420 is a potent and selective bromodomain-containing protein 4 (BRD4) inhibitor with IC50 values of 27 nM against BRD4 BD1 and 32 nM against BRD4 BD2[1].
CAS Number
2229039-45-4
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Epigenetic Reader Domain
Type
Reference compound
Related Pathways
Epigenetics
Applications
COVID-19-anti-virus
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/e-z-zl0420.html
Solubility
10 mM in DMSO
Smiles
O=C1NC2=C(C=C(/N=N/C3=CC(C)=C(O)C=C3N)C=C2)CC1
Molecular Formula
C16H16N4O2
Molecular Weight
296.32
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Zhiqing Liu, et al. Discovery of potent and selective BRD4 inhibitors capable of blocking TLR3-induced acute airway inflammation. Eur J Med Chem. 2018 May 10;151:450-461.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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Alternative Products

CatalogName
MBS3844586-01(E)-ZL0420
A20136-5(E) -ZL0420 5mg
A20136-50(E) -ZL0420 50mg
A20136-10(E) -ZL0420 10mg
A20136-100(E) -ZL0420 100mg
A20136-25(E) -ZL0420 25mg
BA4716-5ZL0420
A16829-200ZL0420 200mg

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