GPCR agonist-2

• Description:

  GPCR agonist-2 (Compound 5j) is a GPCR GPR109b (HM74) agonist, with a pEC50 value of 6.51. GPCR agonist-2 can be used for research of lipid disorders[1].

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  GPR109A

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/gpcr-agonist-2.html

• Purity:

  99.93

• Solubility:

  DMSO : 125 mg/mL (ultrasonic; warming; heat to 60°C)

• Smiles:

  O=C (O) C1=CC=C (NC2CC2) C ([N+] ([O-]) =O) =C1

• Molecular Formula:

  C10H10N2O4

• Molecular Weight:

  222.20

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]Skinner PJ, et al. 3-Nitro-4-amino benzoic acids and 6-amino nicotinic acids are highly selective agonists of GPR109b. Bioorg Med Chem Lett. 2007 Dec 1;17 (23) :6619-22.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, protect from light)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  291528-35-3