GPCR agonist-2

CAT: 0804-HY-47823-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-47823-01Size:5 mg
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Description
GPCR agonist-2 (Compound 5j) is a GPCR GPR109b (HM74) agonist, with a pEC50 value of 6.51. GPCR agonist-2 can be used for research of lipid disorders[1].
CAS Number
[291528-35-3]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
GPR109A
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/gpcr-agonist-2.html
Purity
99.93
Solubility
DMSO : 125 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(O)C1=CC=C(NC2CC2)C([N+]([O-])=O)=C1
Molecular Formula
C10H10N2O4
Molecular Weight
222.20
Precautions
H302, H315, H319, H335
References & Citations
[1]Skinner PJ, et al. 3-Nitro-4-amino benzoic acids and 6-amino nicotinic acids are highly selective agonists of GPR109b. Bioorg Med Chem Lett. 2007 Dec 1;17 (23) :6619-22.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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