THR-β agonist 2

• Description:

  THR-β agonist 2 is a potent agonist of THR-β. THR-β agonist 2 has the potential for the research of metabolic diseases such as obesity, hyperlipidemia, hypercholesterolemia, diabetes and other conditions such as steatosis and non-alcoholic steatohepatitis (NASH), atherosclerosis and other related conditions and diseases (extracted from patent WO2021121210A1, compound 3) [1].

• UNSPSC:

  12352005

• Target:

  Thyroid Hormone Receptor

• Type:

  Reference compound

• Related Pathways:

  Vitamin D Related/Nuclear Receptor

• Applications:

  Metabolism-sugar/lipid metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/thr-β-agonist-2.html

• Purity:

  99.31

• Solubility:

  DMSO : 350 mg/mL (ultrasonic)

• Smiles:

  N#CC1=NN(C2=CC(Cl)=C(OC3=NNC(C4=C3C=CC=C4)=O)C(Cl)=C2)C(NC1=O)=O

• Molecular Formula:

  C18H8Cl2N6O4

• Molecular Weight:

  443.20

• References & Citations:

  [1]Fanglong Yang, et al. Heterocyclic derivatives, their preparation methods and their application in medicine. Patent WO2021121210A1.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, 3 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [2440027-77-8]