SORT-PGRN interaction inhibitor 1

• Product Name Alternative:

  BMS-387032, Mutagenic Impurity of Tenofovir Disoproxil (Standard); Tenofovir Impurity 2 (Standard)

• CAS Number:

  100957-85-5

• UNSPSC Description:

  SORT-PGRN interaction inhibitor 1 is a potent inhibitor of the sortilin-progranulin interaction with an IC50 of 2 μM[1].

• Target Antigen:

  Neurotensin Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein;Neuronal Signaling

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/sort-pgrn-interaction-inhibitor-1.html

• Purity:

  99.17

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  O=C(C1=CC(C(C)(C)C)=NN1CC2=CC=CC=C2)O

• Molecular Weight:

  258.32

• References & Citations:

  [1]Shawn J Stachel, et al. Identification of potent inhibitors of the sortilin-progranulin interaction. Bioorg Med Chem Lett. 2020 Sep 1;30(17):127403.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported