ERCC1/XPA interaction inhibitor 1

CAT:

804-HY-161623

Size:

Inquire

Price:

Ask

For price, please contact [email protected]

UNSPSC Description: ERCC1/XPA interaction inhibitor 1 (compound 27o) is a potent ERCC1/XPA67-80 interaction inhibitor with an EC50 value of 4.7 µM. ERCC1/XPA interaction inhibitor 1 has the potential for the research of DNA damaging agents and overcoming resistance to platinum-based chemotherapy[1].
Target Antigen: DNA/RNA Synthesis
Type: Reference compound
Related Pathways: Cell Cycle/DNA Damage
Applications: Cancer-programmed cell death
Field of Research: Cancer
Assay Protocol: https://www.medchemexpress.com/ercc1-xpa-interaction-inhibitor-1.html
Solubility: 10 mM in DMSO
Smiles: O=C(NC1=CC=CC=C1C(O)CSC2=NC(C)=CC(C)=C2C#N)CC3=CC=C(Cl)C=C3
Molecular Weight: 451.97
References & Citations: [1]Obermann R, et al. Small Molecule Antagonists of the DNA Repair ERCC1/XPA Protein-Protein Interaction. C ChemMedChem. 2024 Apr 16;19(8):e202300648.
Shipping Conditions: Room temperature
Clinical Information: No Development Reported

Cat	Name
HY-161623	ERCC1/XPA interaction inhibitor 1
HY-115213-02	SORT-PGRN interaction inhibitor 1
HY-156237-03	Beclin1-ATG14L interaction inhibitor 1
HY-156237-01	Beclin1-ATG14L interaction inhibitor 1
HY-149898-04	HA-CD44 interaction inhibitor 1
HY-149898-02	HA-CD44 interaction inhibitor 1
HY-149898-01	HA-CD44 interaction inhibitor 1
HY-102090-03	B7/CD28 interaction inhibitor 1
HY-102090-01	B7/CD28 interaction inhibitor 1
HY-124137	Runx1-CBFβ interaction inhibitor 1

Cat	Name
T3189-50mg	B7/CD28 interaction inhibitor 1
T28219-1mg	NusB-NusE interaction inhibitor-1
T3189-1mg	B7/CD28 interaction inhibitor 1
T9044-1mg	SORT-PGRN interaction inhibitor 1
T9044-5mg	SORT-PGRN interaction inhibitor 1
T28219-10mg	NusB-NusE interaction inhibitor-1
MBS3612902-02	SORT-PGRN interaction inhibitor 1
MBS5822779	SORT-PGRN interaction Inhibitor 2
MBS5821417	Beclin1-ATG14L interaction Inhibitor 1
T9044-1g	SORT-PGRN interaction inhibitor 1