SORT-PGRN interaction inhibitor 1

CAT:

804-HY-115213-01

Size:

10 mM / 1 mL

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Product Name Alternative: Mutagenic Impurity of Tenofovir Disoproxil (Standard); Tenofovir Impurity 2 (Standard)
CAS Number: 100957-85-5
UNSPSC Description: SORT-PGRN interaction inhibitor 1 is a potent inhibitor of the sortilin-progranulin interaction with an IC50 of 2 μM[1].
Target Antigen: Neurotensin Receptor
Type: Reference compound
Related Pathways: GPCR/G Protein;Neuronal Signaling
Field of Research: Neurological Disease
Assay Protocol: https://www.medchemexpress.com/sort-pgrn-interaction-inhibitor-1.html
Purity: 99.17
Solubility: DMSO : 100 mg/mL (ultrasonic)
Smiles: O=C(C1=CC(C(C)(C)C)=NN1CC2=CC=CC=C2)O
Molecular Weight: 258.32
References & Citations: [1]Shawn J Stachel, et al. Identification of potent inhibitors of the sortilin-progranulin interaction. Bioorg Med Chem Lett. 2020 Sep 1;30(17):127403.
Shipping Conditions: Room Temperature
Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
Clinical Information: No Development Reported

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