SORT-PGRN interaction inhibitor 3

• CAS Number:

  2691846-87-2

• UNSPSC Description:

  SORT-PGRN interaction inhibitor 3 (Compound 13) is a SORT-PGRN interaction inhibitor (IC50: 0.17 μM). SORT-PGRN interaction inhibitor 3 can be used for research of neurodegenerative diseases[1].

• Target Antigen:

  Neurotensin Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein;Neuronal Signaling

• Applications:

  Neuroscience-Neurodegeneration

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/sort-pgrn-interaction-inhibitor-3.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CC(C)(C)CC[C@@H](C(O)=O)NC(C1=CC(Cl)=CC(Cl)=C1)=O

• Molecular Weight:

  332.22

• References & Citations:

  [1]Stachel SJ, et al. Identification of potent inhibitors of the sortilin-progranulin interaction. Bioorg Med Chem Lett. 2020 Sep 1;30(17):127403.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported