SORT-PGRN interaction inhibitor 2

• CAS Number:

  1008233-79-1

• UNSPSC Description:

  SORT-PGRN interaction inhibitor 2 is a SORT-PGRN inhibitor that can decreases SORT1 protein expression and increases extracellular PGRN secretion in mammalian cell lines. SORT-PGRN interaction inhibitor 2 can be used for neurological disease research[1].

• Target Antigen:

  Others

• Type:

  Reference compound

• Related Pathways:

  Others

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/sort-pgrn-interaction-inhibitor-2.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CC1CN(CCOC2=CC(C)=CC=C2C(C)(C)C)CCC1

• Molecular Weight:

  289.46

• References & Citations:

  [1]Lee WC, et.al. Targeted manipulation of the sortilin-progranulin axis rescues progranulin haploinsufficiency. Hum Mol Genet. 2014 Mar 15;23(6):1467-78.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported