LU-005i

CAT: 0804-HY-148732-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-148732-01Size:1 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
LU-005i is a potent inhibitor of β5i subunit of immunoproteasomes (IC50 = 6.6 nM), selective over β5c subunit (IC50 = 287 nM) [1].
CAS Number
[1620107-33-6]
UNSPSC
12352005
Target
Proteasome
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/lu-005i.html
Purity
98.24
Solubility
DMSO : ≥ 100 mg/mL
Smiles
COC(C=C1)=CC=C1C[C@H](NC([C@H](C)NC(CN2CCOCC2)=O)=O)C(N[C@@H](CC3CCCCC3)C([C@]4(CO4)C)=O)=O
Molecular Formula
C31H46N4O7
Molecular Weight
586.72
References & Citations
[1]Rezvan Moallemian, et al. Immunoproteasome inhibitor DPLG3 attenuates experimental colitis by restraining NF-κB activation.Biochem Pharmacol. 2020 Jul:177:113964.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-120783Lu AF58801
HY-132981-01Lu AF27139
HY-100366-01Lu AF21934
HY-180320Lu AF58786
HY-14408Lu AA47070
HY-14409Lu AA41063
HY-133910-01Lu AE98134
HY-118363-01Lu AE51090
HY-107729-01Lu AA33810
HY-117697Lu AF11205

Alternative Products

CatalogName
TRC-L215970-100MGLU 005i
T84755-01LU-005i
ARC0470Lu-65
255710-01LU AA33810
453947-01Lu AE58054
T36813-01Lu AE98134
T202885-01Lu 19005
MBS5782473LU 49700
MBS5775491Lu AF58801
BUP03206-01Lu AF27139

Popular Products