LU 2443

• UNSPSC Description:

  LU 2443 is an orally active antiepileptic mesoionic. LU 2443 is extensively absorbed, in the maximum 18% are eliminated unabsorbed in rats. The half-time of the activity in plasma is 13.17 h[1].

• Target Antigen:

  Drug Metabolite

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/lu-2443.html

• Smiles:

  S=C1SC(C2=CC=CC=C2)=[N+](C)[N-]1

• Molecular Weight:

  208.30

• References & Citations:

  [1]Neidlein R, et al. Biotransformation und Pharmakokinetik von mesoionischem Didehydro-4-methyl-5-phenyl-1,3,4-thiadiazolidin-2-thion (LU 2443). Untersuchungen zur Pharmakokinetik an Ratten [Biotransformation and pharmacokinetics of mesionic didehydro-4-methyl-5-phenyl-1,3,4-thiadiazolidine-2-thione (LU 2443). Studies on the pharmacokinetics in rats]. Arzneimittelforschung. 1982;32(11):1447-52.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  19703-86-7