LU 2443

• Description :

  LU 2443 is an orally active antiepileptic mesoionic. LU 2443 is extensively absorbed, in the maximum 18% are eliminated unabsorbed in rats. The half-time of the activity in plasma is 13.17 h[1].

• UNSPSC :

  12352005

• Target :

  Drug Metabolite

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/lu-2443.html

• Smiles :

  S=C1SC(C2=CC=CC=C2)=[N+](C)[N-]1

• Molecular Formula :

  C9H8N2S2

• Molecular Weight :

  208.30

• References & Citations :

  [1]Neidlein R, et al. Biotransformation und Pharmakokinetik von mesoionischem Didehydro-4-methyl-5-phenyl-1,3,4-thiadiazolidin-2-thion (LU 2443) . Untersuchungen zur Pharmakokinetik an Ratten [Biotransformation and pharmacokinetics of mesionic didehydro-4-methyl-5-phenyl-1,3,4-thiadiazolidine-2-thione (LU 2443) . Studies on the pharmacokinetics in rats]. Arzneimittelforschung. 1982;32 (11) :1447-52.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [19703-86-7]