Lu AE98134

• Target :

  Others|||Sodium Channel

• Related Pathways :

  Others|||Membrane transporter/Ion channel

• Bioactivity :

  Lu AE98134, an activator of voltage-gated sodium channels, acts as a partly selective positive modulator of Nav1.1 channels and also increases the activity of Nav1.2 and Nav1.5 channels while not affecting Nav1.4, Nav1.6, and Nav1.7 channels. Lu AE98134 can be used to analyze pathophysiological functions of the Nav1.1 channel in various central nervous system diseases, including cognitive restoring in schizophrenia, et al[1].

• Smiles :

  CCCCNS(=O)(=O)c1ccc(OC)c(c1)-c1nnc2c3ccccc3c(C)nn12

• Molecular Formula :

  C21H23N5O3S

• Molecular Weight :

  425.5

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  849000-18-6