7,3′,5′-Trihydroxyflavanone

• Description :

  7,3′,5′-Trihydroxyflavanone, a flavanoid derivative, induces the apoptotic cell death of MCF-7 cells by increasing Bax expression level. 7,3′,5′-Trihydroxyflavanone also exhibits antioxidant activity[1][2].

• UNSPSC :

  12352005

• Target :

  Apoptosis

• Type :

  Natural Products

• Related Pathways :

  Apoptosis

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/7-3-5-trihydroxyflavanone.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C1C[C@@H](C2=CC(O)=CC(O)=C2)OC3=CC(O)=CC=C13

• Molecular Formula :

  C15H12O5

• Molecular Weight :

  272.25

• References & Citations :

  [1]Abdullah H, et, al. A natural compound from Hydnophytum formicarium induces apoptosis of MCF-7 cells via up-regulation of Bax. Cancer Cell Int. 2010 May 4;10:14.|[2]Tsvetkov DE, et, al. Components of the extracts of the knot wood of Dalbergia Sissoo Linn. and their antioxidant activity. Russian Chemical Bulletin. 2019 Sep; 68:1756-1762.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported

• CAS Number :

  [847375-46-6]