Products for Research Use Only
RegisterLogin

6,7,4'-Trihydroxyflavanone

CAT: 0804-HY-N9602Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-N9602Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
6,7,4'-Trihydroxyflavanone is a compound with multiple pharmacological activities, including anti-rheumatic, anti-ischemic, anti-inflammatory, anti-osteoclastogenic and protective T-cells from METH-induced deactivation. 6,7,4'-Trihydroxyflavanone has shown potential protective effects in neurotoxicity studies and can be used to inhibit patients with neurodegenerative diseases caused by METH. 6,7,4'-Trihydroxyflavanone inhibits METH-induced neurotoxicity by upregulating the Nrf2/HO-1 and PI3K/Akt/mTOR signaling pathways. 6,7,4'-Trihydroxyflavanone can also induce Nrf2 nuclear translocation and HO-1 expression, further enhancing its protective effect on neuronal cells[1].
CAS Number
189689-31-4
UNSPSC
12352005
Target
Akt
Type
Natural Products
Related Pathways
PI3K/Akt/mTOR
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/6-7-4-trihydroxyflavanone.html
Smiles
O=C1C2=CC(O)=C(O)C=C2O[C@H](C3=CC=C(C=C3)O)C1
Molecular Formula
C15H12O5
Molecular Weight
272.25
References & Citations
[1]6,7,4'-Trihydroxyflavanone Mitigates Methamphetamine-Induced Neurotoxicity in SH-SY5y Cells via Nrf2/heme Oxyganase-1 and PI3K/Akt/mTOR Signaling Pathways
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

Related Products

CatalogName
HY-N9391-017,3′,5′-Trihydroxyflavanone
HY-111806-013,7,4'-Trihydroxyflavone
HY-N2736-013′,4′,7-Trihydroxyflavone
HY-133951-014',6,7-Trimethoxyisoflavone
HY-N11484-015,6,7-Trihydroxyflavone-7-O-β-D-glucuronopyranoside
HY-Y0260-014-Chloro-6,7-dimethoxyquinazoline
HY-W269179-014-Bromomethyl-6,7-dimethoxycoumarin
HY-20456-014-Chloro-6,7-dimethoxyquinoline
HY-D0063-016,7-Diethoxy-4-methylcoumarin
HY-N88494-Methyl-6,7-methylenedioxycoumarin

Alternative Products

CatalogName
PHA68931-016,7,4'-Trihydroxyflavanone
WAA91399-013',4',7-Trihydroxyflavanone
TN7858-017,2',4'-Trihydroxyflavanone
36117021Naringenin (4',5,7-Trihydroxyflavanone)
MBS58010937,3?,5?-Trihydroxyflavanone
FM65712-013'-Methoxy-5,7,4'-trihydroxyflavanone
T409407,3′,5′-Trihydroxyflavanone
MBS6031489-01Naringenin (4',5,7-Trihydroxyflavanone, Naringetol, Salipurpol)
T24805-014',5,7-Trihydroxyflavanone mixture of enetiomers 97%
TRC-A579515-100MG4,4,5,5,6,6,7,7,7-Nonafluoroheptanoic Acid

Popular Products