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3,7,4'-Trihydroxyflavone

CAT: 0804-HY-111806-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-111806-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
3,7,4'-Trihydroxyflavone (5-Deoxykampferol) is a flavonoid compound that can be isolated from the stems of Rhus javanica var. roxburghiana. 3,7,4'-Trihydroxyflavone has the effect of cleaving DNA in the presence of copper ions. 3,7,4'-Trihydroxyflavone also has anti-inflammatory and antioxidant activities and can scavenge various reactive oxygen species (ROS) and reactive nitrogen species (RNS) [1][2].
CAS Number
2034-65-3
Product Name Alternative
5-Deoxykampferol; Resokaempferol
UNSPSC
12352005
Target
DNA/RNA Synthesis; Leukotriene Receptor; Reactive Oxygen Species (ROS)
Type
Natural Products
Related Pathways
Cell Cycle/DNA Damage; GPCR/G Protein; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/3,7,4_acute_-Trihydroxyflavone.html
Concentration
10mM
Purity
99.44
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1C(O)=C(C2=CC=C(O)C=C2)OC3=CC(O)=CC=C13
Molecular Formula
C15H10O5
Molecular Weight
270.24
References & Citations
[1]Lin CN, et al. Flavonoids with DNA strand-scission activity from Rhus javanica var. roxburghiana. Fitoterapia. 2008 Jan;79 (1) :32-6. Epub 2007 Aug 9.|[2]Gomes A, et al. Trihydroxyflavones with antioxidant and anti-inflammatory efficacy. Biofactors. 2012 Sep-Oct;38 (5) :378-86.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
LTB4

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