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SC-68376

CAT: 0804-HY-112333Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-112333Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SC-68376 is a potent, reversible, ATP-competitive, and selective inhibitor of p38 MAP kinase inhibitor[1][2][3].
CAS Number
318480-82-9
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
P38 MAPK
Type
Reference compound
Related Pathways
MAPK/ERK Pathway
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/sc-68376.html
Smiles
CC1=NC(C2=CC=CC=C2)=C(O1)C3=CC=NC=C3
Molecular Formula
C15H12N2O
Molecular Weight
236.27
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]H. Bosch, et al. Nanoparticulate compositions of mitogen-activated protein (MAP) kinase inhibitors. US20030181411A1. 2005-12-07.|[2]Ermert M, et al. Cyclooxygenase-2-dependent and thromboxane-dependent vascular and bronchial responses are regulated via p38 mitogen-activated protein kinase in control and endotoxin-primed rat lungs. Lab Invest. 2003;83 (3) :333-347. |[3]Kooijman R, et al. IGF-I stimulates IL-8 production in the promyelocytic cell line HL-60 through activation of extracellular signal-regulated protein kinase. Cell Signal. 2003;15 (12) :1091-1098.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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