CZL-S092

• Target:

  PLK

• Related Pathways:

  Cell Cycle/Checkpoint

• Bioactivity:

  CZL-S092 is a PLK4 inhibitor with exceptional selectivity for other PLK4 family members (PLK1, PLK2, and PLK3), exhibiting an IC50 of 0.9 nM. It demonstrates antineuroblastoma activity in vitro (IMR-32, IC50 = 1.143 ?M) and shows good oral bioavailability in vivo (SD rats, F = 22.1%) . CZL-S092 is applicable in research on various cancers, including neuroblastoma.

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C