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SR-16157

CAT: 0804-HY-123773Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-123773Size:1 Each
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Description
SR-16157 (NSC 732011; HLX-801) is a dual-action steroid sulfatase (STS) inhibitor (IC50 = 0.1 uM) and selective ERĪ± modulator. SR-16157 exhibits STS inhibitory and anti-estrogenic effects in breast cancer cells. SR-16157 may be used in breast cancer research[1].
CAS Number
[943344-76-1]
Product Name Alternative
NSC 732011; HLX-801
UNSPSC
12352005
Target
Estrogen Receptor/ERR; Steroid Sulfatase
Related Pathways
Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Field of Research
Cancer
Smiles
O=S(OC1=CC=C2[C@@]3([H])CC[C@]4(C)[C@@H](CCOCCN(CC)CC)CC[C@@]4([H])[C@]3([H])[C@H](C)CC2=C1)(N)=O
Molecular Formula
C27H44N2O4S
Molecular Weight
492.71
References & Citations
[1]Rasmussen LM, et al. A novel dual-target steroid sulfatase inhibitor and antiestrogen: SR 16157, a promising agent for the therapy of breast cancer. Breast Cancer Res Treat. 2007 Dec;106 (2) :191-203.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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