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GTD2A rabbit pAb

CAT: 0855-ES15862-01Size: 50 µLDry Ice: NoHazardous: No
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Background
This gene is one of several closely related genes on chromosome 7 encoding proteins containing helix-loop-helix motifs. These proteins may function as regulators of transcription. The encoded protein is unique in that its C-terminus is derived from CHARLIE8 transposable element sequence. This gene is located in a region of chromosome 7 that is deleted in Williams-Beuren syndrome, and loss of this locus may contribute to the cognitive phenotypes observed in this disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Description
This gene is one of several closely related genes on chromosome 7 encoding proteins containing helix-loop-helix motifs. These proteins may function as regulators of transcription. The encoded protein is unique in that its C-terminus is derived from CHARLIE8 transposable element sequence. This gene is located in a region of chromosome 7 that is deleted in Williams-Beuren syndrome, and loss of this locus may contribute to the cognitive phenotypes observed in this disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],
Product Name Alternative
General transcription factor II-I repeat domain-containing protein 2A (GTF2I repeat domain-containing protein 2A) (Transcription factor GTF2IRD2-alpha)
UniProt
Q86UP8
Swiss Prot
Q86UP8
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from human GTD2A AA range: 529-579
Target
GTD2A
Clonality
Polyclonal
Source
Rabbit
Applications
WB
Concentration
1 mg/ml
Dilution
WB 1:500-2000
Buffer
-20°C/1 year
Molecular Weight
105kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
105kD
Fragment
IgG
Subcellular Location
Nucleus.
Other Product Names
General transcription factor II-I repeat domain-containing protein 2A (GTF2I repeat domain-containing protein 2A) (Transcription factor GTF2IRD2-alpha)
Gene ID (Human)
84163

UniProtKB · Q86UP8

General transcription factor II-I repeat domain-containing protein 2A

GTD2A_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q86UP8
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
GTF2IRD2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
GTF2I repeat domain-containing protein 2A
EC number
—
Processing
—
Secondary accessions
A0A0A0MSY2, A8K5W6, B3KUZ2, Q69G40, Q6EKI8, Q6EKI9, Q6NVW2, Q6P7N8, Q86WX4, Q8ND85, Q8NDE5
Protein keywords

Coding sequence diversity

Alternative splicing

Molecular function

DNA-binding

Cellular component

Nucleus

Technical term

Reference proteome

Domain

Repeat

Biological process

TranscriptionTranscription regulation

Disease

Williams-Beuren syndrome

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