GTD2A Antibody

• Background:

  GTD2A is unusual in that its coding sequence is mostly derived from Charlie8 repeat elements. However, there is mRNA and EST evidence to suggest that this gene is transcribed, and the encoded protein has a homolog in mouse, with which it shares 78% sequence identity. The exact function of this gene product is not known. It is inferred to be a transcription factor based on the presence of GTF2I-like repeats (containing helix-loop-helix motifs), also found in other proteins such as GTF2IRD1 and GTF2I. These three genes are clustered together on chr 7q11.23.

• NCBI Gene ID:

  84163

• Swiss Prot:

  Q86UP8

• Accession Number:

  Q86UP8

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This GTD2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 812-841 amino acids from the C-terminal region of human GTD2A.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  107 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  GTF2IRD2

• NCBI Official Name:

  General transcription factor II-I repeat domain-containing protein 2A

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Hinsley, T.A., et al. Protein Sci. 13 (10) :2588-2599 (2004)

• Background Reference 02:

  Makeyev, A.V., et al. Proc. Natl. Acad. Sci. U.S.A. 101 (30) :11052-11057 (2004)

• Background Reference 03:

  Tipney, H.J., et al. Eur. J. Hum. Genet. 12 (7) :551-560 (2004)

• Other Product Names:

  General transcription factor II-I repeat domain-containing protein 2A, GTF2I repeat domain-containing protein 2A, Transcription factor GTF2IRD2-alpha, GTF2IRD2, GTF2IRD2A

• Tested Applications:

  WB, Flow

• Protein ID:

  187607027

• Physical Properties:

  Liquid