GLPG0634 analog

CAT: 0804-HY-13961-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-13961-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GLPG0634 analog (Compoun 176) is a broad spectrum JAK inhibitor with IC50 values of [1].
CAS Number
[1206101-20-3]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
JAK
Type
Reference compound
Related Pathways
Epigenetics; JAK/STAT Signaling; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/GLPG0634-analog.html
Concentration
10mM
Purity
98.07
Solubility
DMSO : ≥ 53 mg/mL
Smiles
O=C(C1CC1)NC2=NN3C(C4=CC=C(OCC5=CC=C(C#N)N=C5)C=C4)=CC=CC3=N2
Molecular Formula
C23H18N6O2
Molecular Weight
410.43
Precautions
H302, H315, H319, H335
References & Citations
[1]Christel Jeanne Marie Menet, et al. Novel compounds useful for the treatment of degenerative and inflammatory diseases. WO2010010190A1.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
JAK1; JAK2; JAK3; Tyk2

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