GLPG0634 analog

• Description:

  GLPG0634 analog (Compoun 176) is a broad spectrum JAK inhibitor with IC50 values of [1].

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  JAK

• Type:

  Reference compound

• Related Pathways:

  Epigenetics; JAK/STAT Signaling; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/GLPG0634-analog.html

• Concentration:

  10mM

• Purity:

  98.07

• Solubility:

  DMSO : ≥ 53 mg/mL

• Smiles:

  O=C(C1CC1)NC2=NN3C(C4=CC=C(OCC5=CC=C(C#N)N=C5)C=C4)=CC=CC3=N2

• Molecular Formula:

  C23H18N6O2

• Molecular Weight:

  410.43

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]Christel Jeanne Marie Menet, et al. Novel compounds useful for the treatment of degenerative and inflammatory diseases. WO2010010190A1.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, protect from light, stored under nitrogen)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  JAK1; JAK2; JAK3; Tyk2

• CAS Number:

  [1206101-20-3]