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ML228 analog

CAT: 0804-HY-29090Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-29090Size:1 Each
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Description
ML228 analog is an analog of ML228 (HY-12754) . ML228 is a potent activator of HIF[1].
CAS Number
[1357026-36-8]
UNSPSC
12352005
Target
HIF/HIF Prolyl-Hydroxylase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ml228-analog.html
Solubility
10 mM in DMSO
Smiles
CC(C)(C)C(C=C1)=CC=C1CNC2=C(C3=CC=CC=C3)N=NC(C4=CC=CC=N4)=N2
Molecular Formula
C25H25N5
Molecular Weight
395.50
References & Citations
[1]Theriault JR, et al. Discovery of a new molecular probe ML228: an activator of the hypoxia inducible factor (HIF) pathway. Bioorg Med Chem Lett. 2012 Jan 1;22 (1) :76-81.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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