ML228 analog

• Description :

  ML228 analog is an analog of ML228 (HY-12754) . ML228 is a potent activator of HIF[1].

• UNSPSC :

  12352005

• Target :

  HIF/HIF Prolyl-Hydroxylase

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/ml228-analog.html

• Solubility :

  10 mM in DMSO

• Smiles :

  CC(C)(C)C(C=C1)=CC=C1CNC2=C(C3=CC=CC=C3)N=NC(C4=CC=CC=N4)=N2

• Molecular Formula :

  C25H25N5

• Molecular Weight :

  395.50

• References & Citations :

  [1]Theriault JR, et al. Discovery of a new molecular probe ML228: an activator of the hypoxia inducible factor (HIF) pathway. Bioorg Med Chem Lett. 2012 Jan 1;22 (1) :76-81.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [1357026-36-8]