Harmaline analog

• Description:

  Harmaline analog (compound 3) is a selective cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 0.145 μM[1].

• UNSPSC:

  12352005

• Target:

  COX

• Type:

  Reference compound

• Related Pathways:

  Immunology/Inflammation

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/harmaline-analog.html

• Solubility:

  10 mM in DMSO

• Smiles:

  ClC1=CC=C(CN2C3=C(C4=C2C(C)=NCC4)C=C(OC)C=C3)C=C1

• Molecular Formula:

  C20H19ClN2O

• Molecular Weight:

  338.83

• References & Citations:

  [1]Uddin MJ, et al. Harmaline Analogs as Substrate-Selective Cyclooxygenase-2 Inhibitors. ACS Med Chem Lett. 2020 Feb 14;11 (10) :1881-1885.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [2411677-02-4]