PROTAC CDK9/CycT1 Degrader-2

PROTAC CDK9/CycT1 Degrader-2

• CAS Number: 3020773-91-2
• UNSPSC Description: PROTAC CDK9/CycT1 Degrader-2 is a inhibitor of CDK9, with the IC50 of 45 nM[1].
• Target Antigen: CDK
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/protac-cdk9-cyct1-degrader-2.html
• Solubility: 10 mM in DMSO
• Smiles: O=C1OC2=CC(OCCCN3CCC(CC3)C(NC4=NC=C(S4)SCC5=NC=C(O5)C(C)(C)C)=O)=CC(O)=C2C(C)=C1
• Molecular Weight: 612.76
• References & Citations: [1]Harald Gollnick, et al. Degradation of Cyclin-Dependent Kinase 9/Cyclin T1 by Optimized Microtubule-Associated Protein 1 Light Chain 3 Beta-Recruiting Coumarin Analogs. Expert Opin Pharmacother. 2008 Oct;9(15):2699-706.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported