PROTAC CDK9 Degrader-1

• UNSPSC Description:

  PROTAC CDK9 Degrader-1 is a PROTAC connected by ligands for Cereblon and CDK as a selective CDK9 degrader.

• Target Antigen:

  CDK; PROTACs

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage;PROTAC

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/PROTAC_6.html

• Purity:

  98.03

• Solubility:

  DMSO : ≥ 104 mg/mL

• Smiles:

  O=C(CC1=CC=C(OCCCCCOC2=CC=CC(C(N3C4C(NC(CC4)=O)=O)=O)=C2C3=O)C=C1)NC5=CC(C6CCC6)=NN5

• Molecular Weight:

  613.66

• References & Citations:

  [1]Robb CM, et al. Chemically induced degradation of CDK9 by a proteolysis targeting chimera (PROTAC). Chem Commun (Camb). 2017 Jul 4;53(54):7577-7580.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  2118356-96-8