MDL 105519

MDL 105519

• Description:

  MDL 105519 is a potent and selective antagonist of glycine binding to the NMDA receptor.

• UNSPSC:

  12352005

• Target:

  IGluR

• Type:

  Reference compound

• Related Pathways:

  Membrane Transporter/Ion Channel; Neuronal Signaling

• Applications:

  Neuroscience-Neurodegeneration

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/MDL-105519.html

• Concentration:

  10mM

• Purity:

  99.67

• Solubility:

  DMSO : 17 mg/mL (ultrasonic; warming)

• Smiles:

  O=C(O)C(N1)=C(/C=C(C2=CC=CC=C2)/C(O)=O)C3=C1C=C(Cl)C=C3Cl

• Molecular Formula:

  C18H11Cl2NO4

• Molecular Weight:

  376.19

• References & Citations:

  [1]Baron BM, et al. Pharmacological characterization of MDL 105,519, an NMDA receptor glycine site antagonist. Eur J Pharmacol. 1997 Apr 4;323 (2-3) :181-92.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  NMDA Receptor

• CAS Number:

  [161230-88-2]