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Diheptanoyl Thio-PC

CAT: 0804-HY-W713925-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-W713925-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Diheptanoyl Thio-PC is a substrate for all phospholipase A2s (PLA2s) with the exception of cPLA2 and PAF-acetyl hydrolase (PAF-AH) .1 Interaction of this compound with a PLA2 results in cleavage of the sn-2 fatty acid generating a free thiol on the lysophospholipid. This free thiol can be detected using chromogenic substrates such as DTNB (Ellman’s reagent) and DTP.
CAS Number
89019-63-6
UNSPSC
12352211
Hazard Statement
H225-H350
Target
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/diheptanoyl-thio-pc.html
Smiles
C[N+](C)(C)CCOP(OC[C@H](SC(CCCCCC)=O)CSC(CCCCCC)=O)([O-])=O
Molecular Formula
C22H44NO6PS2
Molecular Weight
513.69
Precautions
P210-P233-P240-P241-P242-P243-P280-P303+P361+P353-P370+P378-P403+P235-P405-P501
References & Citations
[1]Hendrickson, et al. Chiral synthesis of a dithiolester analog of phosphatidylcholine as a substrate for the assay of phospholipase A2. J. Lipid Res. 24 (11), 1532-1537 (1983) .
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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