Palmitoyl thio-PC

• Target:

  Others

• Related Pathways:

  Others

• Bioactivity:

  Thioester analogs of glycerophospholipids, in combination with Ellman's reagent, are convenient colorimetric substrates for the measurement of phospholipase (PL) activity. Palmitoyl thio-PC is a chromogenic PLA2 substrate that contains a palmitoyl thioester at the sn-2 position of the glycerol backbone. Hydrolysis of the thioester by PLA2 yields a free thiol that reacts readily with DTNB (Ellman's reagent) giving a bright yellow product with an absorbance maximum at 412 nm. Palmitoyl thio-PC has been used to measure bee venom sPLA2 activity in a phospholipid:Triton X-100 mixed micelle system.

• Smiles:

  CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)SC(=O)CCCCCCCCCCCCCCC

• Molecular Formula:

  C40H80NO7PS

• Molecular Weight:

  750.11

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  113881-60-0