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Palmitoyl thio-PC

CAT: 0931-T37244-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T37244-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
113881-60-0
Target
Others
Related Pathways
Others
Bioactivity
Thioester analogs of glycerophospholipids, in combination with Ellman's reagent, are convenient colorimetric substrates for the measurement of phospholipase (PL) activity. Palmitoyl thio-PC is a chromogenic PLA2 substrate that contains a palmitoyl thioester at the sn-2 position of the glycerol backbone. Hydrolysis of the thioester by PLA2 yields a free thiol that reacts readily with DTNB (Ellman's reagent) giving a bright yellow product with an absorbance maximum at 412 nm. Palmitoyl thio-PC has been used to measure bee venom sPLA2 activity in a phospholipid:Triton X-100 mixed micelle system.
Smiles
CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)SC(=O)CCCCCCCCCCCCCCC
Molecular Formula
C40H80NO7PS
Molecular Weight
750.11
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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