1,4-PBIT (dihydrobromide)

1,4-PBIT (dihydrobromide)

• CAS Number: 157254-60-9
• UNSPSC Description: 1,4-PBIT (1,4-PB-ITU) dihydrobromide (compound 46) is a potent nitric oxide synthases (NOS) inhibitor, with Ki values of 7.6 nM, 360 nM, and 16 nM for the inducible (iNOS), endothelial (eNOS), and neuronal (nNOS) isozymes, respectively[1].
• Target Antigen: NO Synthase
• Type: Reference compound
• Related Pathways: Immunology/Inflammation
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/1-4-pbit-dihydrobromide.html
• Smiles: NC(SCCC1=CC=C(CCSC(N)=N)C=C1)=N.[H]Br.[H]Br
• Molecular Weight: 444.25
• References & Citations: [1]E P Garvey, et al. Potent and selective inhibition of human nitric oxide synthases. Inhibition by non-amino acid isothioureas. J Biol Chem. 1994 Oct 28;269(43):26669-76.
• Shipping Conditions: Room temperature