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Impentamine (dihydrobromide)

CAT: 0804-HY-107564Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-107564Size:1 Each
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Description
Impentamine dihydrobromide (VUF 4702 dihydrobromide) is a histamine H3 receptor antagonist with potential antihistamine activity. Impentamine dihydrobromide shows the strongest selective H3 antagonism among a series of 4 (5) - (ω-aminoalkyl) -1H-imidazole compounds. The pA2 value of impentamine dihydrobromide is 8.4, showing its high efficacy in guinea pig jejunum. Impentamine dihydrobromide has a specific antagonistic binding site with the H3 receptor[1].
CAS Number
149629-70-9
Product Name Alternative
VUF 4702 (dihydrobromide)
UNSPSC
12352005
Target
Histamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/impentamine-dihydrobromide.html
Smiles
NCCCCCC1=CN=CN1.[H]Br.[H]Br
Molecular Formula
C8H17Br2N3
Molecular Weight
315.05
References & Citations
[1]Homologs of histamine as histamine H3 receptor antagonists: a new potent and selective H3 antagonist, 4 (5) - (5-aminopentyl) -1H-imidazole
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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