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CAY10589

CAT: 0804-HY-117008-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-117008-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CAY10589 is an inhibitor of mPGES-1, an enzyme induced during inflammatory responses. CAY10589 has no significant effect on the differentiation of BM myeloid precursor cells into M2-like TAMs[1][2].
CAS Number
[1077626-52-8]
UNSPSC
12352005
Target
PGE synthase
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/cay10589.html
Solubility
10 mM in DMSO
Smiles
O=C(C(CCCCCC)SC1=NC(Cl)=CC(NCC2=CC=C(C3=CC=CC=C3)C=C2)=N1)O
Molecular Formula
C25H28ClN3O2S
Molecular Weight
470.03
References & Citations
[1]Wiegard A, et al. Pyrrole alkanoic acid derivatives as nuisance inhibitors of microsomal prostaglandin E2 synthase-1. Eur J Med Chem. 2012 Feb;48:153-63.|[2]Li L, et al. Targeting the lipid metabolic reprogramming of tumor-associated macrophages: A novel insight into cancer immunotherapy. Cell Oncol (Dordr) . 2023 Sep 30.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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