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CAY10580

CAT: 0804-HY-135259Size: 1 mg (14.64 mM x 200 μL in Ethanol)Dry Ice: NoHazardous: No
CAT#:0804-HY-135259Size:1 mg (14.64 mM x 200 μL in Ethanol)
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Description
CAY10580 is a potent and selective prostaglandin EP4 receptor agonist (Ki=35 nM) [1].
CAS Number
[64054-40-6]
UNSPSC
12352005
Hazard Statement
H225, H319
Target
Prostaglandin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/cay10580.html
Concentration
14.64 mM * 200 μL in Ethanol
Purity
97.40
Solubility
10 mM in DMSO
Smiles
O=C(O)CCCCCCN1C(CCC(O)CCCCC)CCC1=O
Molecular Formula
C19H35NO4
Molecular Weight
341.49
Precautions
H225, H319
References & Citations
[1]Billot X, et al. Discovery of a potent and selective agonist of the prostaglandin EP4 receptor. Bioorg Med Chem Lett. 2003;13 (6) :1129-1132. |[2]Olesen ET, et al. Vasopressin-independent targeting of aquaporin-2 by selective E-prostanoid receptor agonists alleviates nephrogenic diabetes insipidus. Proc Natl Acad Sci U S A. 2011;108 (31) :12949-12954. |[3]Ying F, et al. EP4 emerges as a novel regulator of bile acid synthesis and its activation protects against hypercholesterolemia. Biochim Biophys Acta Mol Cell Biol Lipids. 2018;1863 (9) :1029-1040.
Shipping Conditions
Blue Ice
Storage Conditions
Solution, -20°C, 2 years
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
EP

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