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CAY10581

CAT: 0804-HY-113568Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-113568Size:1 mg
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Description
CAY10581, a pyranonaphthoquinone derivative, is a highly specific and reversible uncompetitive IDO Inhibitor with an IC50 of 55 nM[1][2].
CAS Number
[1018340-07-2]
UNSPSC
12352005
Target
Indoleamine 2,3-Dioxygenase (IDO)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cay10581.html
Solubility
10 mM in DMSO
Smiles
O=C1C2=C(C(C3=C1C=CC=C3)=O)[C@@H]([C@@H](C(C)(O2)C)O)NCC4=CC=CC=C4
Molecular Formula
C22H21NO4
Molecular Weight
363.41
References & Citations
[1]Sanjeev Kumar, et al. Indoleamine 2,3-dioxygenase is the anticancer target for a novel series of potent naphthoquinone-based inhibitors. J Med Chem. 2008 Mar 27;51 (6) :1706-18.|[2]Siddaraju V Boregowda, et al. A Clinical Indications Prediction Scale Based on TWIST1 for Human Mesenchymal Stem Cells. EBioMedicine. 2015 Dec 24;4:62-73.|[3]Sanjeev Kumar, et al. Indoleamine 2,3-dioxygenase is the anticancer target for a novel series of potent naphthoquinone-based inhibitors. J Med Chem. 2008 Mar 27;51 (6) :1706-18.|[4]Siddaraju V Boregowda, et al. A Clinical Indications Prediction Scale Based on TWIST1 for Human Mesenchymal Stem Cells. EBioMedicine. 2015 Dec 24;4:62-73.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
IDO

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