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Epothilone A (Standard)

CAT: 0804-HY-13503RSize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-13503RSize:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Epothilone A (Standard) is the analytical standard of Epothilone A. This product is intended for research and analytical applications. Epothilone A is a competitive inhibitor of the binding of [3H] paclitaxel to tubulin polymers, with a Ki of 0.6-1.4 μM.
CAS Number
152044-53-6
Product Name Alternative
Epo A (Standard)
UNSPSC
12352005
Target
Apoptosis; Microtubule/Tubulin; Reference Standards
Type
Reference Standards
Related Pathways
Apoptosis; Cell Cycle/DNA Damage; Cytoskeleton; Others
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/epothilone-a-standard.html
Smiles
O=C(C[C@H](O)C1(C)C)O[C@H](/C(C)=C/C2=CSC(C)=N2)C[C@]3([H])O[C@]3([H])CCC[C@H](C)[C@H](O)[C@@H](C)C1=O
Molecular Formula
C26H39NO6S
Molecular Weight
493.66
References & Citations
[1]Kowalski RJ, et al. Activities of the microtubule-stabilizing agents epothilones A and B with purified tubulin and in cells resistant to paclitaxel (Taxol (R) ) . J Biol Chem. 1997 Jan 24;272 (4) :2534-41.|[2]Cheng KL, et al. Novel microtubule-targeting agents - the epothilones. Biologics. 2008 Dec;2 (4) :789-811.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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