Epothilone E

• Description :

  Epothilone E is a related compound of epothilone, which inhibits microtubule protein function and blocks cell division, and has anti-tumor activity[1].

• UNSPSC :

  12352005

• Target :

  Microtubule/Tubulin

• Type :

  Reference compound

• Related Pathways :

  Cell Cycle/DNA Damage; Cytoskeleton

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/epothilone-e.html

• Solubility :

  10 mM in DMSO

• Smiles :

  OCC1=NC(/C=C([C@@H]2C[C@@]3([H])[C@](CCC[C@@H]([C@@H]([C@H](C(C(C)([C@H](CC(O2)=O)O)C)=O)C)O)C)([H])O3)\C)=CS1

• Molecular Formula :

  C26H39NO7S

• Molecular Weight :

  509.66

• References & Citations :

  [1]K. C. Nicolaou, et al. Total synthesis of epothilone E and analogues with modified side chains through the Stille coupling reaction[J]. Angewandte Chemie International Edition, 1998, 37 (1‐2) : 84-87.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [201049-37-8]