Epothilone E

• UNSPSC Description:

  Epothilone E is a related compound of epothilone, which inhibits microtubule protein function and blocks cell division, and has anti-tumor activity[1].

• Target Antigen:

  Microtubule/Tubulin

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage;Cytoskeleton

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/epothilone-e.html

• Solubility:

  10 mM in DMSO

• Smiles:

  OCC1=NC(/C=C([C@@H]2C[C@@]3([H])[C@](CCC[C@@H]([C@@H]([C@H](C(C(C)([C@H](CC(O2)=O)O)C)=O)C)O)C)([H])O3)\C)=CS1

• Molecular Weight:

  509.66

• References & Citations:

  [1]K. C. Nicolaou, et al. Total synthesis of epothilone E and analogues with modified side chains through the Stille coupling reaction[J]. Angewandte Chemie International Edition, 1998, 37(1‐2): 84-87.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  201049-37-8