Epothilone F

• UNSPSC Description:

  Epothilone F is a Microtubule/Tubulin-stabilizing agent with anti-tumor activity. Epothilone F inhibits the proliferation of breast cancer cells, non-small cell lung cancer cells, drug-resistant ovarian cancer cells[1].

• Target Antigen:

  Microtubule/Tubulin

• Type:

  Natural Products

• Related Pathways:

  Cell Cycle/DNA Damage;Cytoskeleton

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/epothilone-f.html

• Purity:

  99.00

• Solubility:

  DMSO : 133.33 mg/mL (ultrasonic)

• Smiles:

  O=C(O[C@@H](C[C@H]1[C@@](C)(CCC[C@@H]([C@@H]([C@H](C(C2(C)C)=O)C)O)C)O1)/C(C)=C/C3=CSC(CO)=N3)C[C@@H]2O

• Molecular Weight:

  523.68

• References & Citations:

  [1]Flörsheimer A, et al. Epothilones and their analogues-a new class of promising microtubule inhibitors[J]. Expert Opinion on Therapeutic Patents, 2001, 11(6): 951-968.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C (Powder, protect from light)

• Clinical Information:

  No Development Reported

• CAS Number:

  208518-52-9