Canthin-6-one

• Description:

  Canthin-6-one is an indole alkaloid, displays antibacterial and anti-inflammatory activities[1][2].

• UNSPSC:

  12352005

• Hazard Statement:

  H302-H315-H319-H335

• Target:

  Akt; Bacterial; COX; NF-κB; NO Synthase

• Type:

  Natural Products

• Related Pathways:

  Anti-infection; Immunology/Inflammation; NF-κB; PI3K/Akt/mTOR

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection; Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/canthin-6-one.html

• Purity:

  99.92

• Solubility:

  DMSO : 25 mg/mL (ultrasonic)

• Smiles:

  O=C1N2C3=C(N=CC=C3C4=C2C=CC=C4)C=C1

• Molecular Formula:

  C14H8N2O

• Molecular Weight:

  220.23

• Precautions:

  P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

• References & Citations:

  [1]O'Donnell G, Gibbons S. Antibacterial activity of two canthin-6-one alkaloids from Allium neapolitanum. Phytother Res. 2007;21 (7) :653-657. |[2]Cho SK, et al., Anti-inflammatory Effects of Canthin-6-one Alkaloids from Ailanthus altissima. Planta Med. 2018 May;84 (8) :527-535.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, sealed storage, away from moisture and light)

• Scientific Category:

  Natural Products

• Clinical Information:

  No Development Reported

• CAS Number:

  479-43-6