4-Hydroxycanthin-6-one

• Description:

  4-Hydroxycanthin-6-one is a novel quinoline alkaloid isolated from the stem bark of the tree Ailanthus altissima. Five other known compounds were also found in the study. The structures of the new compounds were determined by interpretation of physical and spectroscopic data, and their absolute configurations were determined by electronic circular dichroism spectroscopy and quantum chemical calculations. These compounds showed significant inhibitory activity against lipopolysaccharide (LPS) -induced nitric oxide (NO) production in RAW 264.7 cells, showing potential anti-inflammatory properties[1].

• UNSPSC:

  12352005

• Target:

  Others

• Type:

  Natural Products

• Related Pathways:

  Others

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/4-hydroxycanthin-6-one.html

• Smiles:

  O=C1C=C(C2=NC=CC3=C2N1C4=CC=CC=C34)O

• Molecular Formula:

  C14H8N2O2

• Molecular Weight:

  236.23

• References & Citations:

  [1]Kim HM, et al. A New Canthinone-Type Alkaloid Isolated from Ailanthus altissima Swingle. Molecules. 2016 May 16;21 (5) :642.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Natural Products

• Clinical Information:

  No Development Reported

• CAS Number:

  106941-27-9