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5-Methoxycanthin-6-one

CAT: 804-HY-N9194Size: 1 mgDry Ice: NoHazardous: No
1 mgSelected
PRICE
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
5-Methoxycanthin-6-one is an orally active inhibitor of Leishmania strains. 5-Methoxycanthin-6-one shows cytotoxicity with an IC50 of 5.44 μg/mL against Ailanthus altissima cells[1][2].
CAS Number
[15071-56-4]
UNSPSC
12352005
Target
Parasite
Type
Natural Products
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/5-methoxycanthin-6-one.html
Solubility
10 mM in DMSO
Smiles
O=C1N2C3=C(N=CC=C3C4=C2C=CC=C4)C=C1OC
Molecular Formula
C15H10N2O2
Molecular Weight
250.25
References & Citations
[1]Ferreira ME, et al. Leishmanicidal activity of two canthin-6-one alkaloids, two major constituents of Zanthoxylum chiloperone var. angustifolium. J Ethnopharmacol. 2002 May;80 (2-3) :199-202.|[2]Anderson LA, et al. Production of cytotoxic canthin-6-one alkaloids by Ailanthus altissima plant cell cultures. J Nat Prod. 1983 May-Jun;46 (3) :374-8.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Leishmania

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