11-Hydroxycanthin-6-one

• Description :

  11-Hydroxycanthin-6-one, a canthin-6-one (HY-N3536) alkaloid, is an antitumor agent which shows potent cytotoxic activity[1][2].

• UNSPSC :

  12352005

• Hazard Statement :

  H302-H312-H332

• Target :

  Drug Derivative

• Type :

  Natural Products

• Related Pathways :

  Others

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/11-hydroxycanthin-6-one.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C1N2C3=C(N=CC=C3C4=C2C=CC=C4O)C=C1

• Molecular Formula :

  C14H8N2O2

• Molecular Weight :

  236.23

• Precautions :

  P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501

• References & Citations :

  [1]Fukamiya N, et, al. Antitumor agents: LXXXVII. Cytotoxic antileukemic canthin-6-one alkaloids from Brucea antidysenterica and the structure activity relationships of their related derivatives. Planta Med. 1987 Apr;53 (2) :140-3.|[2]Miyake K, et, al. Canthin-6-one alkaloids and a tirucallanoid from Eurycoma longifolia and their cytotoxic activity against a human HT-1080 fibrosarcoma cell line. Nat Prod Commun. 2010 Jan;5 (1) :17-22.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported

• CAS Number :

  [75969-83-4]