β-Estradiol-6-one 6-(O-carboxymethyloxime)

• UNSPSC Description:

  β-Estradiol-6-one 6-(O-carboxymethyloxime) is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

• Target Antigen:

  PROTAC Linkers

• Type:

  Reference compound

• Related Pathways:

  PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/β-estradiol-6-one-6-o-carboxymethyloxime.html

• Purity:

  99.67

• Solubility:

  10 mM in DMSO

• Smiles:

  OC1=CC=C(C/2=C1)[C@@]3([H])CC[C@@]([C@@H](O)CC4)(C)[C@]4([H])[C@]3([H])CC2=N/OCC(O)=O

• Molecular Weight:

  359.42

• References & Citations:

  [1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  35048-47-6