HEPES

• Description:

  HEPES, a nonvolatile zwitterionic chemical buffering agent, is broadly applied in cell culture. HEPES is effective at pH 6.8 to 8.2. HEPES is also a potent inducer of lysosome biogenesis[1][2][3].

• UNSPSC:

  12352200

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  Biochemical Assay Reagents

• Type:

  Biochemical Assay Reagents

• Related Pathways:

  Others

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/hepes.html

• Purity:

  99.94

• Solubility:

  H2O : 250 mg/mL (ultrasonic)

• Smiles:

  O=S (CCN1CCN (CCO) CC1) (O) =O

• Molecular Formula:

  C8H18N2O4S

• Molecular Weight:

  238.30

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]Suzuki T, et al. Nonvolatile buffer coating of titanium to prevent its biological aging and for drug delivery. Biomaterials. 2010;31 (18) :4818-4828.|[2]Sledź P, et al. An experimental charge density of HEPES. Acta Crystallogr B. 2010;66 (Pt 4) :482-492.|[3]Tol MJ, et al. HEPES activates a MiT/TFE-dependent lysosomal-autophagic gene network in cultured cells: A call for caution. Autophagy. 2018;14 (3) :437-449.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  Store at room temperature 3 years

• Scientific Category:

  Biochemical Assay Reagents

• Clinical Information:

  No Development Reported

• CAS Number:

  7365-45-9