C-82

CAT: 0804-HY-112359-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-112359-01Size:1 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
C-82 is a second-generation specific CBP/β-catenin antagonist, which inhibits the binding between β-catenin and CBP and increases the binding between β-catenin and p300[1].
CAS Number
[1422253-37-9]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Wnt; β-catenin
Type
Reference compound
Related Pathways
Stem Cell/Wnt
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/C-82.html
Purity
99.91
Solubility
DMSO : 62.5 mg/mL (ultrasonic)
Smiles
O=C(N1N(C)CC(N([C@H]2CC3=CC=C(O)C=C3)[C@]1([H])[C@H](C)N(CC4=CC=CC5=C4N=CC=C5)C2=O)=O)NCC6=CC=CC=C6
Molecular Formula
C33H34N6O4
Molecular Weight
578.66
Precautions
H302, H315, H319, H335
References & Citations
[1]Osawa Y, et al. Inhibition of Cyclic Adenosine Monophosphate (cAMP) -response Element-binding Protein (CREB) -binding Protein (CBP) /β-Catenin Reduces Liver Fibrosis in Mice. EBioMedicine. 2015 Oct 8;2 (11) :1751-8.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2

Related Products

CatalogName
HY-P1836C-Reactive Protein (CRP) (77-82)
HY-168462α-Glucosidase-IN-82
HY-136241-01OT-82
HY-149401EGFR-IN-82
HY-162902ALK5-IN-82
HY-169922HDAC-IN-82
HY-170938AChE-IN-82
HY-U00028T 82
HY-163265HSD17B13-IN-82
HY-136499-01DI-82

Alternative Products

CatalogName
M26079-01C-82
CCP2225-01C-Reactive Protein (77-82)
RM-C061882-01Cefuroxime Impurity 82; Deacetoxycephalosporin C
B2018450C-Reactive Protein (CRP) 77-82
T204291-01α-Glucosidase-IN-82
T200604-01ALK5-IN-82
207115OT-82
1211137RECORD indicators +82°C, VE=50
TP1516-01C-Reactive Protein (CRP) (77-82)
MBS5783934-01RTI 82

Popular Products