Flecainide-d3

• Description :

  Flecainide-d3 is the deuterium labeled Flecainide. Flecainide is an orally active antiarrhythmic agent. Flecainide can block sodium channels and inhibit calcium ion release mediated by the cardiac ryanodine receptor (RyR2) . Flecainide can be used in the research of diseases such as catecholaminergic polymorphic ventricular tachycardia (CPVT) [1].

• UNSPSC :

  12352005

• Target :

  Isotope-Labeled Compounds; Potassium Channel; Sodium Channel

• Type :

  Isotope-Labeled Compounds

• Related Pathways :

  Membrane Transporter/Ion Channel; Others

• Field of Research :

  Cardiovascular Disease

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(C1=C(C([2H])=C([2H])C(OCC(F)(F)F)=C1[2H])OCC(F)(F)F)NCC2CCCCN2

• Molecular Formula :

  C17H17D3F6N2O3

• Molecular Weight :

  417.36

• References & Citations :

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Isotope-Labeled Compounds

• Clinical Information :

  No Development Reported

• CAS Number :

  [127413-31-4]