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Flecainide (Standard)

CAT: 0804-HY-W010950R-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-W010950R-01Size:5 mg
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Description
Flecainide (Standard) is the analytical standard of Flecainide. This product is intended for research and analytical applications. Flecainide is an orally active antiarrhythmic agent. Flecainide can block sodium channels and inhibit calcium ion release mediated by the cardiac ryanodine receptor (RyR2) . Flecainide can be used in the research of diseases such as catecholaminergic polymorphic ventricular tachycardia (CPVT) [1][2][3].
CAS Number
[54143-55-4]
UNSPSC
12352005
Target
Potassium Channel; Reference Standards; Sodium Channel
Type
Reference Standards
Related Pathways
Membrane Transporter/Ion Channel; Others
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/flecainide-standard.html
Smiles
O=C(C1=CC(OCC(F)(F)F)=CC=C1OCC(F)(F)F)NCC2NCCCC2
Molecular Formula
C17H20F6N2O3
Molecular Weight
414.34
References & Citations
[1]Echt DS, et al. Mortality and morbidity in patients receiving encainide, flecainide, or placebo. The Cardiac Arrhythmia Suppression Trial. N Engl J Med. 1991 Mar 21;324 (12) :781-8.|[2]Aliot E, et al. Twenty-five years in the making: flecainide is safe and effective for the management of atrial fibrillation. Europace. 2011 Feb;13 (2) :161-73.|[3]Allan LD, et al. Flecainide in the treatment of fetal tachycardias. Br Heart J. 1991 Jan;65 (1) :46-8.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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