Flecainide (Standard)

Flecainide (Standard)

• CAS Number: 54143-55-4
• UNSPSC Description: Flecainide (Standard) is the analytical standard of Flecainide. This product is intended for research and analytical applications. Flecainide is a potent and orally active antiarrhythmic agent. Flecainide blocks the cardiac fast inward Na+ current (INa) and the rapid component of the delayed rectifier K+ current. Flecainide prolongs the action potential duration (APD) in ventricular and atrial muscle fibres. Flecainide has the potential for the research of fetal tachycardias[1][2][3].
• Target Antigen: Potassium Channel; Sodium Channel
• Type: Reference Standards
• Related Pathways: Membrane Transporter/Ion Channel
• Field of Research: Cardiovascular Disease
• Assay Protocol: https://www.medchemexpress.com/flecainide-standard.html
• Smiles: O=C(C1=CC(OCC(F)(F)F)=CC=C1OCC(F)(F)F)NCC2NCCCC2
• Molecular Weight: 414.34
• References & Citations: [1]Echt DS, et al. Mortality and morbidity in patients receiving encainide, flecainide, or placebo. The Cardiac Arrhythmia Suppression Trial. N Engl J Med. 1991 Mar 21;324(12):781-8.|[2]Aliot E, et al. Twenty-five years in the making: flecainide is safe and effective for the management of atrial fibrillation. Europace. 2011 Feb;13(2):161-73.|[3]Allan LD, et al. Flecainide in the treatment of fetal tachycardias. Br Heart J. 1991 Jan;65(1):46-8.
• Shipping Conditions: Room temperature