Flecainide (Standard)

• Description:

  Flecainide (Standard) is the analytical standard of Flecainide. This product is intended for research and analytical applications. Flecainide is an orally active antiarrhythmic agent. Flecainide can block sodium channels and inhibit calcium ion release mediated by the cardiac ryanodine receptor (RyR2) . Flecainide can be used in the research of diseases such as catecholaminergic polymorphic ventricular tachycardia (CPVT) [1][2][3].

• UNSPSC:

  12352005

• Target:

  Potassium Channel; Reference Standards; Sodium Channel

• Type:

  Reference Standards

• Related Pathways:

  Membrane Transporter/Ion Channel; Others

• Field of Research:

  Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/flecainide-standard.html

• Smiles:

  O=C(C1=CC(OCC(F)(F)F)=CC=C1OCC(F)(F)F)NCC2NCCCC2

• Molecular Formula:

  C17H20F6N2O3

• Molecular Weight:

  414.34

• References & Citations:

  [1]Echt DS, et al. Mortality and morbidity in patients receiving encainide, flecainide, or placebo. The Cardiac Arrhythmia Suppression Trial. N Engl J Med. 1991 Mar 21;324 (12) :781-8.|[2]Aliot E, et al. Twenty-five years in the making: flecainide is safe and effective for the management of atrial fibrillation. Europace. 2011 Feb;13 (2) :161-73.|[3]Allan LD, et al. Flecainide in the treatment of fetal tachycardias. Br Heart J. 1991 Jan;65 (1) :46-8.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference Standards

• CAS Number:

  [54143-55-4]