Donepezil HCl

• Description:

  Donepezil Hydrochloride (Donepezil HCL) is a novel, potent and selective inhibitor of acetylcholinesterase (AChE), an enzyme possibly involved in cognitive dysfunction of patients suffering Alzheimer’s disease (AD), with the half maximal inhibition concentration IC50 value of 6.7 nM.

• Purity:

  ≥ 99%

• Solubility:

  Insoluble in EtOH; insoluble in DMSO; ≥ 10.4 mg/mL in H2O. For obtaining a higher solubility, please warm the tube at 37°C and shake it in the ultrasonic bath for a while.

• Molecular Formula:

  C24H30ClNO3

• Shipping Conditions:

  Room Temperature (continental US) or Gel Packs

• Storage Conditions:

  At least 6 months at -20°C.

• Calculated Molecular Weight:

  416 Da

• CAS Number:

  120011-70-3