SARS-CoV-2 Spike S1 Domain (High Purity)

• Description:

  SARS-CoV-2 Spike S1 Domain _x000D_ Catalog number: B2010507_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Amount: 100 ug_x000D_ Molecular Weight or Concentration: 76 kDa_x000D_ Supplied as: Lyophilized Powder_x000D_ Applications: molecular component of many serological and antigenic assays for SARS-CoV-2_x000D_ Storage: -20℃_x000D_ Keywords: Spike S1, S1 protein_x000D_ Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ Download SARS-CoV-2 Brochure_x000D_ _x000D_ References:_x000D_ 1: Weisblum Y, Schmidt F, Zhang F, DaSilva J, Poston D, Lorenzi JC, Muecksch F,_x000D_ Rutkowska M, Hoffmann HH, Michailidis E, Gaebler C, Agudelo M, Cho A, Wang Z,_x000D_ Gazumyan A, Cipolla M, Luchsinger L, Hillyer CD, Caskey M, Robbiani DF, Rice CM,_x000D_ Nussenzweig MC, Hatziioannou T, Bieniasz PD. Escape from neutralizing antibodies_x000D_ by SARS-CoV-2 spike protein variants. Elife. 2020 Oct 28;9:e61312._x000D_ _x000D_ 2: Walls AC, Park YJ, Tortorici MA, Wall A, McGuire AT, Veesler D. Structure,_x000D_ Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein. Cell. 2020 Apr_x000D_ 16;181(2):281-292.e6._x000D_ _x000D_ 3: Barnes CO, Jette CA, Abernathy ME, Dam KA, Esswein SR, Gristick HB, Malyutin_x000D_ AG, Sharaf NG, Huey-Tubman KE, Lee YE, Robbiani DF, Nussenzweig MC, West AP Jr,_x000D_ Bjorkman PJ. SARS-CoV-2 neutralizing antibody structures inform therapeutic_x000D_ strategies. Nature. 2020 Dec;588(7839):682-687._x000D_ _x000D_ 4: Wang Q, Zhang Y, Wu L, Niu S, Song C, Zhang Z, Lu G, Qiao C, Hu Y, Yuen KY,_x000D_ Wang Q, Zhou H, Yan J, Qi J. Structural and Functional Basis of SARS-CoV-2 Entry_x000D_ by Using Human ACE2. Cell. 2020 May 14;181(4):894-904.e9._x000D_ _x000D_ 5: Ou X, Liu Y, Lei X, Li P, Mi D, Ren L, Guo L, Guo R, Chen T, Hu J, Xiang Z,_x000D_ Mu Z, Chen X, Chen J, Hu K, Jin Q, Wang J, Qian Z. Characterization of spike_x000D_ glycoprotein of SARS-CoV-2 on virus entry and its immune cross-reactivity with_x000D_ SARS-CoV. Nat Commun. 2020 Mar 27;11(1):1620._x000D_ _x000D_ 6: Xia X. Domains and Functions of Spike Protein in Sars-Cov-2 in the Context of_x000D_ Vaccine Design. Viruses. 2021 Jan 14;13(1):109._x000D_ _x000D_ 7: Barnes CO, West AP Jr, Huey-Tubman KE, Hoffmann MAG, Sharaf NG, Hoffman PR,_x000D_ Koranda N, Gristick HB, Gaebler C, Muecksch F, Lorenzi JCC, Finkin S, Hägglöf T,_x000D_ Hurley A, Millard KG, Weisblum Y, Schmidt F, Hatziioannou T, Bieniasz PD, Caskey_x000D_ M, Robbiani DF, Nussenzweig MC, Bjorkman PJ. Structures of Human Antibodies_x000D_ Bound to SARS-CoV-2 Spike Reveal Common Epitopes and Recurrent Features of_x000D_ Antibodies. Cell. 2020 Aug 20;182(4):828-842.e16._x000D_ _x000D_ 8: Daly JL, Simonetti B, Klein K, Chen KE, Williamson MK, Antón-Plágaro C,_x000D_ Shoemark DK, Simón-Gracia L, Bauer M, Hollandi R, Greber UF, Horvath P, Sessions_x000D_ RB, Helenius A, Hiscox JA, Teesalu T, Matthews DA, Davidson AD, Collins BM,_x000D_ Cullen PJ, Yamauchi Y. Neuropilin-1 is a host factor for SARS-CoV-2 infection._x000D_ Science. 2020 Nov 13;370(6518):861-865._x000D_ _x000D_ 9: Wu Y, Li C, Xia S, Tian X, Kong Y, Wang Z, Gu C, Zhang R, Tu C, Xie Y, Yang_x000D_ Z, Lu L, Jiang S, Ying T. Identification of Human Single-Domain Antibodies_x000D_ against SARS-CoV-2. Cell Host Microbe. 2020 Jun 10;27(6):891-898.e5._x000D_ 10: Buzhdygan TP, DeOre BJ, Baldwin-Leclair A, Bullock TA, McGary HM, Khan JA,_x000D_ Razmpour R, Hale JF, Galie PA, Potula R, Andrews AM, Ramirez SH. The SARS-CoV-2_x000D_ spike protein alters barrier function in 2D static and 3D microfluidic in-vitro_x000D_ models of the human blood-brain barrier. Neurobiol Dis. 2020 Dec;146:105131._x000D_ _x000D_ Products Related to SARS-CoV-2 Spike S1 Domain: SARS-CoV-2

• Short Description:

  Catalog Number: B2010507 (100 ug)

• Weight:

  0.15

• Length:

  2

• Width:

  0.5

• Height:

  0.5

• Height :

  0.5