SARS-CoV-2 Spike RBD Gamma Variant

• Description:

  SARS-CoV-2 Spike RBD Gamma Variant_x000D_ Catalog number: B2010500_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Amount: 100 ug_x000D_ Molecular Weight or Concentration: 27 kDa_x000D_ Supplied as: Lyophilized Powder_x000D_ Applications: molecular component of many serological and antigenic assays for SARS-CoV-2 and its variants_x000D_ Storage: -20℃_x000D_ Keywords: Gamma Variant Spike, P1 Spike RBD, P1 RBD_x000D_ Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ Download SARS-CoV-2 Brochure_x000D_ _x000D_ References:_x000D_ 1: Sahin U, Muik A, Derhovanessian E, Vogler I, Kranz LM, Vormehr M, Baum A,_x000D_ Pascal K, Quandt J, Maurus D, Brachtendorf S, Lörks V, Sikorski J, Hilker R,_x000D_ Becker D, Eller AK, Grützner J, Boesler C, Rosenbaum C, Kühnle MC, Luxemburger_x000D_ U, Kemmer-Brück A, Langer D, Bexon M, Bolte S, Karikó K, Palanche T, Fischer B,_x000D_ Schultz A, Shi PY, Fontes-Garfias C, Perez JL, Swanson KA, Loschko J, Scully IL,_x000D_ Cutler M, Kalina W, Kyratsous CA, Cooper D, Dormitzer PR, Jansen KU, Türeci Ö._x000D_ COVID-19 vaccine BNT162b1 elicits human antibody and T_H1 T cell_x000D_ responses. Nature. 2020 Oct;586(7830):594-599._x000D_ _x000D_ 2: Kim S, Liu Y, Lei Z, Dicker J, Cao Y, Zhang XF, Im W. Differential_x000D_ Interactions Between Human ACE2 and Spike RBD of SARS-CoV-2 Variants of Concern._x000D_ bioRxiv [Preprint]. 2021 Jul 26:2021.07.23.453598._x000D_ _x000D_ 3: Zahradník J, Marciano S, Shemesh M, Zoler E, Harari D, Chiaravalli J, Meyer_x000D_ B, Rudich Y, Li C, Marton I, Dym O, Elad N, Lewis MG, Andersen H, Gagne M, Seder_x000D_ RA, Douek DC, Schreiber G. SARS-CoV-2 variant prediction and antiviral drug_x000D_ design are enabled by RBD in vitro evolution. Nat Microbiol. 2021_x000D_ Sep;6(9):1188-1198._x000D_ _x000D_ 4: Choi JA, Goo J, Yang E, Jung DI, Lee S, Rho S, Jeong Y, Park YS, Park H, Moon_x000D_ YH, Park U, Seo SH, Lee H, Lee JM, Cho NH, Song M, Kim JO. Cross-Protection_x000D_ against MERS-CoV by Prime-Boost Vaccination Using Viral Spike DNA and Protein. J_x000D_ Virol. 2020 Nov 23;94(24):e01176-20._x000D_ _x000D_ 5: Mohammadi M, Shayestehpour M, Mirzaei H. The impact of spike mutated variants_x000D_ of SARS-CoV2 [Alpha, Beta, Gamma, Delta, and Lambda] on the efficacy of subunit_x000D_ recombinant vaccines. Braz J Infect Dis. 2021 Aug 17;25(4):101606._x000D_ _x000D_ 6: Barton MI, MacGowan SA, Kutuzov MA, Dushek O, Barton GJ, van der Merwe PA._x000D_ Effects of common mutations in the SARS-CoV-2 Spike RBD and its ligand the human_x000D_ ACE2 receptor on binding affinity and kinetics. Elife. 2021 Aug 26;10:e70658._x000D_ _x000D_ 7: Aleem A, Akbar Samad AB, Slenker AK. Emerging Variants of SARS-CoV-2 And_x000D_ Novel Therapeutics Against Coronavirus (COVID-19). 2021 Jul 18. In: StatPearls_x000D_ [Internet]. Treasure Island (FL): StatPearls Publishing; 2021 Jan–._x000D_ _x000D_ 8: Chen L, Zody MC, Di Germanio C, Martinelli R, Mediavilla JR, Cunningham MH,_x000D_ Composto K, Chow KF, Kordalewska M, Corvelo A, Oschwald DM, Fennessey S,_x000D_ Zetkulic M, Dar S, Kramer Y, Mathema B, Germer S, Stone M, Simmons G, Busch MP,_x000D_ Maniatis T, Perlin DS, Kreiswirth BN. Emergence of Multiple SARS-CoV-2 Antibody_x000D_ Escape Variants in an Immunocompromised Host Undergoing Convalescent Plasma_x000D_ Treatment. mSphere. 2021 Aug 25;6(4):e0048021._x000D_ _x000D_ 9: Tian F, Tong B, Sun L, Shi S, Zheng B, Wang Z, Dong X, Zheng P. N501Y_x000D_ mutation of spike protein in SARS-CoV-2 strengthens its binding to receptor_x000D_ ACE2. Elife. 2021 Aug 20;10:e69091._x000D_ 10: Chen J, Gao K, Wang R, Wei GW. Revealing the Threat of Emerging SARS-CoV-2_x000D_ Mutations to Antibody Therapies. J Mol Biol. 2021 Sep 3;433(18):167155. _x000D_ _x000D_ Products Related to SARS-CoV-2 Spike RBD Gamma Variant : SARS-CoV-2

• Short Description:

  Catalog Number: B2010500 (100 ug)

• Weight:

  0.15

• Length:

  2

• Width:

  0.5

• Height:

  0.5

• Height :

  0.5